Since the 1950s, Dr Abram Hoffer, MD, PhD, healed countless hearts and minds with his discovery of megadose niacin (vitamin B3) therapy for schizophrenia. This heralded the onset of megavitamin therapy, starting as a niacin/vitamin C treatment. As the therapy developed, other nutrients and health considerations were included, per unique individual requirements.
Eventually niacin and megavitamin treatment contributed to the recovery or great improvement of tens of thousands of people with schizophrenia: voices and psychosis gone, rare, or significantly muted. Niacin may also play a prominent role in bipolar therapy, especially if voices or anxiety are involved.
My earlier blogposts discuss this further: https://www.boragebooks.com/schizophrenia-blog.html
For details and studies, see my books, Natural Healing for Schizophrenia and Natural Healing for Bipolar Disorder at https://www.boragebooks.com/