Dr. Walsh later suggested that the primary imbalance in low histamine (histapenic) patients was actually brain overmethylation accompanied by insufficient folate. Blood histamine is still the best test for this condition.
Symptoms of histapenia in bipolars
Common symptoms in histapenic bipolars can include anxiety, panic, hyperactivity, racing thoughts, hypomania or mania, and general overstimulation. And, especially with low niacin and zinc, and high copper: paranoia, and psychotic mania. Manic or hypomanic periods may be more prevalent than in other biotypes, though depression also occurs.
Descriptions of both mental and physical symptoms of histapenia can be viewed online in the sample pages from my schizophrenic book (though note, these pages focus more on schizophrenic manifestations of histapenia) on the boragebooks.com website at:
For further details see my book, Natural Healing for Bipolar Disorder.
Reminder: This information is presented for educational purposes only, and is not intended for diagnostic or treatment purposes. If you need treatment for mania, bipolar, or any other medical condition, please consult a knowledgeable physician.