Magnesium, is our major natural calcium channel blocker.
Calcium channel blockers (CCBs) inactivate calcium channels, reducing calcium entrance into the cell and increasing levels without (e.g., serum), generally increasing inhibition.
Pharmaceutical trials suggest CCBs support mood stabilization in some bipolars, particularly rapid, and ultra rapid cyclers. and may be most effective in mania, Some studies suggests preventive benefit, particularly when used with lithium.
Magnesium, similarly, controls calcium pumps and blocks calcium uptake to the nerve cell, reducing stimulation, and seems to convey similar effects on mood.
See Natural Healing for Bipolar Disorder for references and further discussion.
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