Since we've been talking of zinc, and vitamins B6 and B3, pyroluria (pyrrole disorder) is probably a good biotype to look at first.
To get some idea, see one of the of the pages on pyroluria in Natural Healing for Bipolar Disorder:
http://boragebooks.com/bipolar_5_pyroluria.html
And for more details, check the following site, including its links to articles by Doctors William J. Walsh, PhD, Carl C. Pfeiffer, PhD, MD, Woody McGinnis, MD, and Jeremy E. Kaslow, MD:
http://www.nutritional-healing.com.au/content/articles-content.php?heading=Pyroluria
For further info on nutrients, health issues, contraindications, etc., see Natural Healing for Bipolar Disorder
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